A selective and sensitive stability-Indicating HPLC method for the validated assay of etoposide from commercial dosage form and polymeric tubular nanocarriers

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A selective and sensitive stability-Indicating HPLC method for the validated assay of etoposide from commercial dosage form and polymeric tubular nanocarriers

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作者：Aslihan Hilal Algan^a ; Mehmet Gumustas^b ; Aysegul Karatas^a ; ^{akaratas@pharmacy.ankara.edu.tr" class="auth_mail" title="E-mail the corresponding author} ; Sibel A. Ozkan^b
关键词：Etoposide ; HPLC ; Validation ; Template wetting method ; Tubular nanocarriers ; Drug release
刊名：Journal of Pharmaceutical and Biomedical Analysis
出版年：2016
出版时间：30 May 2016
年：2016
卷：124
期：Complete
页码：382-389
全文大小：1366 K

文摘

•: Production of etoposide loaded polymeric tubular nanocarriers by template wetting method.
•: Characterization of morphology by SEM and EDX analysis.
•: Determination of drug loading and investigation of in vitro drug release with drug release kinetics.
•: Development and validation of a specific, robust, precise, accurate and simple RP-LC method for the determination of etoposide.
•: Quantification of etoposide from commercial dosage form and produced polymeric tubular nanocarriers.