Proportions of blood-borne Vδ1+ and Vδ2+ T-cells are associated with overall survival of melanoma patients treated with ipilimumab

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Opening Hours
Collections
Help Via Email

Electronic Information Resources

Proportions of blood-borne Vδ1+ and Vδ2+ T-cells are associated with overall survival of melanoma patients treated with ipilimumab

详细信息查看全文

作者：Kilian Wistuba-Hamprecht^a ; ^b ; ^{Kilian.Wistuba-Hamprecht@uni-tuebingen.de" class="auth_mail" title="E-mail the corresponding author} ; Alexander Martens^a ; ^b ; Karin Haehnel^b ; Marnix Geukes Foppen^c ; Jianda Yuan^d ; Michael A. Postow^d ; ^e ; Phillip Wong^d ; Emanuela Romano^f ; Amir Khammari^g ; Brigitte Dreno^g ; Mariaelena Capone^h ; Paolo A. Ascierto^h ; Ilja Demuthⁱ ; ^j ; Elisabeth Steinhagen-Thiessenⁱ ; Anis Larbi^k ; Bastian Schilling^l ; ^m ; Dirk Schadendorf^l ; ^m ; Jedd D. Wolchok^d ; ^e ; Christian U. Blank^c ; Graham Pawelec^b ; ⁿ ; ^o ; Claus Garbe^a ; Benjamin Weide^a
关键词：γδ T-cells ; Melanoma ; Ipilimumab ; Biomarker ; Survival ; Immunotherapy
刊名：European Journal of Cancer
出版年：2016
出版时间：September 2016
年：2016
卷：64
期：Complete
页码：116-126
全文大小：980 K

文摘

•: Frequencies of γδ T-cells are different in melanoma patients and controls.
•: Higher Vδ2+ and lower Vδ1+ T-cell levels in blood are prognostic for survival.
•: Decreasing Vδ2 cells during ipilimumab treatment is associated with poorer survival.

NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.