The role of HPV on the risk of second primary neoplasia in patients with oropharyngeal carcinoma

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• 作者：Marí ; a Martel^a ; Laia Alemany^b ; ^c ; Miren Taberna^b ; ^d ; Marisa Mena^b ; Sara Tous^b ; Silvia Bagué ; ^e ; Xavier Castellsagué ; ^b ; ^c ; ¹ ; Miquel Quer^f ; Xavier Leó ; n^f ; ^g ; ^{xleon@santpau.cat}
• 关键词：Oropharyngeal carcinoma ; Human papillomavirus (HPV) ; Second primary neoplasm ; Tobacco ; Alcohol ; Head and neck cancer
• 刊名：Oral Oncology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：64
• 期：Complete
• 页码：37-43
• 全文大小：665 K
• 卷排序：64

文摘

12.4% of our patients had a HPV-related tumor. HPV-related patients had a lower incidence of second primary neoplasms (SNPs). Differences by HPV-status were even sharper considering tobacco/alcohol-related SPNs. We describe three risk groups of developing a SNPs considering toxic habits and HPV-status. After further validation, it might be justified to limit HPV-related OPC patients’ follow-up.