Bone formation was observed in BCP2 (HA:TCP = 3:7) after 16-week muscle implantation.

BCP2 had elevated density and the least increment of porosity examined by μCT.

Multiple peaks were observed in temporal gene expression patterns, confirmed by IHC.

BCP2 group showed earlier and higher peaks in BMP2, BMPR1A, and OPG expressions.

Time and magnitude of gene expression peaks is crucial in osteoinduction process.