Propofol postsynaptically suppresses stellate neuron excitability in the entorhinal cortex by influencing the HCN and TREK-2 channels

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Propofol postsynaptically suppresses stellate neuron excitability in the entorhinal cortex by influencing the HCN and TREK-2 channels

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作者：Xiaojun Li^a ; Ke Pan^b ; Dan Zhu^a ; Yuping Li^a ; Guocai Tao^a ; ^{guocaitaotmmu@163.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Propofol ; Entorhinal cortex ; HCN channels ; TREK-2 channels ; Stellate neurons
刊名：Neuroscience Letters
出版年：2016
出版时间：21 April 2016
年：2016
卷：619
期：Complete
页码：54-59
全文大小：1310 K

文摘

•: Propofol inhibited the firing rates of stellate neurons in the entorhinal cortex.
•: The propofol-induced inhibition in entorhinal cortex reflected a postsynaptic effect.
•: The inhibitory action of propofol was mediated by influence of HCN and TREK-2 channels.

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