The cytotoxic effect of olaquindox in HepG2 cells was investigated.
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Olaquindox-induced apoptosis involved the GADD45a expression in HepG2 cells.
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Knockdown of GADD45 enhanced olaquindox-induced cell death and apoptosis.
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Knockdown of GADD45 enhanced olaquindox-induced mitochondrial dysfunction.
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