Deleted in malignant brain tumors 1 protein is a potential biomarker of acute respiratory distress syndrome induced by pneumonia

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Deleted in malignant brain tumors 1 protein is a potential biomarker of acute respiratory distress syndrome induced by pneumonia

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作者：Shan Ren^a ; ^b ; ^{rs1226@sina.com" class="auth_mail" title="E-mail the corresponding author} ; Xia Chen^a ; ^{chenxiayuanmeng@163.com" class="auth_mail" title="E-mail the corresponding author} ; Li Jiang^a ; ^{jiangli@sina.com" class="auth_mail" title="E-mail the corresponding author} ; Bo Zhu^a ; ^{zhubo123123@sina.com" class="auth_mail" title="E-mail the corresponding author} ; Qi Jiang^a ; ^{jiangqi7676@sina.com" class="auth_mail" title="E-mail the corresponding author} ; Xiuming Xi^a ; ^{xxm2937@sina.com" class="auth_mail" title="E-mail the corresponding author}
关键词：ARDS ; iTRAQ ; Mass spectrometry ; Biomarkers ; Proteomics
刊名：Biochemical and Biophysical Research Communications
出版年：2016
出版时间：23 September 2016
年：2016
卷：478
期：3
页码：1344-1349
全文大小：469 K

文摘

•: We identified candidate biomarkers for early ARDS diagnosis and risk assessment.
•: Eighteen proteins significantly differed in BALFs of mild and severe ARDS patients.
•: Differential plasma expression of apoA1, SP-A, and DMBT1 was confirmed in ARDS.
•: DMBT1 may be useful for early ARDS diagnosis and predicting disease severity.

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