Naringin promotes fracture healing through stimulation of angiogenesis by regulating the VEGF/VEGFR-2 signaling pathway in osteoporotic rats

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• 作者：Nan Song^a ; ¹ ; Zhihu Zhao^b ; ^c ; ¹ ; Xinlong Ma^b ; ^{gukezzh@126.com} ; Xiaolei Sun^b ; Jianxiong Ma^b ; Fengbo Li^b ; Lei Sun^b ; Jianwei Lv^b
• 关键词：Angiogenesis ; Naringin ; VEGF ; VEGFR-2
• 刊名：Chemico-Biological Interactions
• 出版年：2017
• 出版时间：5 January 2017
• 年：2017
• 卷：261
• 期：Complete
• 页码：11-17
• 全文大小：2924 K
• 卷排序：261

文摘

Naringin promote angiogenesis of fracture healing in osteoporotic rats. Naringin exerts its angiogenetic role via stimulating VEGF/VEGFR-2 signaling. High dose naringin with 300 mg/kg is better than the low dose and middle dose.