Confirming improved detection of gadolinium in bone using in vivo XRF

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• 作者：M.L. Lord^a ; ^{lordml@mcmaster.ca} ; F.E. McNeill^b ; ^{fmcneill@mcmaster.ca} ; J.L. Grä ; fe^c ; ^{james.grafe@ryerson.ca} ; A.L. Galusha^d ; ^e ; ^{aubrey.galusha@health.ny.gov} ; P.J. Parsons^d ; ^e ; ^{patrick.parsons@health.ny.gov} ; M.D. Noseworthy^f ; ^g ; ^h ; ⁱ ; ^{nosewor@mcmaster.ca} ; L. Howard^j ; ^{howardL@mail.amc.edu} ; D.R. Chettle^b ; ^{chettle@mcmaster.ca}
• 关键词：X-ray fluorescence ; ICP-MS ; Gadolinium retention ; Gadolinium in bone ; MRI
• 刊名：Applied Radiation and Isotopes
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：120
• 期：Complete
• 页码：111-118
• 全文大小：548 K
• 卷排序：120

文摘

Methods and experimental results for the latest generation XRF system are presented. An improved minimum detection limit of 1.64–1.72 μg Gd/g plaster for a 30-min measurement is reported. Cross validation of XRF measurements with ICP-MS results in a close agreement between Gd concentration values. XRF system provides promising results and is ready to begin in vivo human measurements.