刊名:Biochimica et Biophysica Acta (BBA) - General Subjects
出版年:2016
出版时间:June 2016
年:2016
卷:1860
期:6
页码:1299-1307
全文大小:1208 K
文摘
•
Contribution of sub-components to inhibitor potency to EV71 3Cpro were investigated
•
P2 groups need to be oriented to bind at the S2 subsite
•
S3 and S4 interacting moieties were required to generate sufficient potency
•
Hydrophobicity in S4 interacting moiety is helpful for cellular uptake
•
The data provide the basis for designing a new generation of inhibitors to 3Cpro
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.