Co-expression networks revealed potential core lncRNAs in the triple-negative breast cancer

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Co-expression networks revealed potential core lncRNAs in the triple-negative breast cancer

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作者：Fan Yang^a ; ¹ ; Ye-huan Liu^a ; ¹ ; Si-yang Dong^a ; Zhi-han Yao^a ; Lin Lv^a ; Rui-min Ma^a ; Xuan-xuan Dai^a ; Jiao Wang^b ; Xiao-hua Zhang^a ; ^{xiaohuazhang2015@sina.com" class="auth_mail" title="E-mail the corresponding author} ; Ou-chen Wang^a ; ^{woconcology2000@163.com" class="auth_mail" title="E-mail the corresponding author}
关键词：TNBC ; triple-negative breast cancer ; LncRNA ; long non-coding RNA ; HER-2 ; human epidermal receptor 2 ; FDR ; false discovery rate ; FC ; Fold Change ; GO ; Gene ontology ; RMST ; rhabdomyosarcoma 2 associated transcript ; TCGA ; The Cancer Genome Atlas ; DEGs ; differentially expressed genes ; KEGG ; Kyoto Encyclopedia of Genes and Genomes ; qRT-PCR ; Quantitative real-time polymerase chain reaction ; SOX2 ; Sex determining region Y-box 2
刊名：Gene
出版年：2016
出版时间：15 October 2016
年：2016
卷：591
期：2
页码：471-477
全文大小：2014 K

文摘

•: 1211 lncRNAs and 3356 mRNAs which were significantly differently expressed in Triple Negative Breast Cancer were detected.
•: Potential core lncRNAs in Triple Negative Breast Cancer were identified by co-expression networks.
•: LncRNA RMST was firstly reported as a prognostic biomarker in breast cancer.

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