Alteration of development and gene expression induced by in ovo-nanoinjection of 3-hydroxybenzo[c]phenanthrene into Japanese medaka (Oryzias latipes) embryos

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• 作者：Kun Chen^a ; Yuki Tsutsumi^a ; Shuhei Yoshitake^a ; Xuchun Qiu^a ; Hai Xu^a ; ^b ; Yasuyuki Hashiguchi^c ; Masato Honda^a ; Kosuke Tashiro^d ; Kei Nakayama^e ; Takeshi Hano^f ; Nobuo Suzuki^g ; Kazuichi Hayakawa^g ; Yohei Shimasaki^a ; Yuji Oshima^a ; ^{yoshima@agr.kyushu-u.ac.jp}
• 关键词：mRNA-Seq ; In ovo-nanoinjection ; PAHs ; Medaka embryo ; Developmental stages ; Heart rate
• 刊名：Aquatic Toxicology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：182
• 期：Complete
• 页码：194-204
• 全文大小：1262 K
• 卷排序：182

文摘

The medaka embryos were exposed to 1 nM 3-OHBcP by in ovo-nanoinjection. Development and heart rate were accelerated in the exposed embryos. The mRNA-Seq results show up-regulated gene expressions due to 1 nM 3-OHBcP exposure. 3-OHBcP may have adverse effects on the development of medaka embryos.