An enantiospecific approach to the synthesis of optically active, trisubstituted allenes from chiral propargylic benzoates and arylboronic acids has been developed. The transformation is catalyzed by a Rh–(P,olefin) complex formed in situ from [{Rh(cod)Cl}<sub>2sub>] and a readily available phosphoramidite ligand. The method furnishes an assortment of diverse allenes in high yields and excellent enantiospecificity under mild conditions.
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.