Cleavage of the C(O)–S Bond of Thioesters by Palladium/Norbornene/Copper Cooperative Catalysis: An Efficient Synthesis of 2-(Arylthio)aryl Ketones

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• 作者：Fenggang Sun ; Miao Li ; Congfa He ; Bin Wang ; Bin Li ; Xianwei Sui ; Zhenhua Gu
• 刊名：Journal of the American Chemical Society
• 出版年：2016
• 出版时间：June 22, 2016
• 年：2016
• 卷：138
• 期：24
• 页码：7456-7459
• 全文大小：418K
• 年卷期：0
• ISSN：1520-5126

文摘

A Pd/norbornene/Cu cooperative catalysis for the efficient synthesis of 2-(arylthio)aryl ketones from aryl halides and thioesters has been developed. The first example of cooperative catalysis by palladium, norbornene, and copper, wherein the C(O)–S bond of thioesters is cleaved by a Pd^II palladacycle with the assistance of CuI, has been observed.