Visible-Light-Promoted Atom Transfer Radical Cyclization of Unactivated Alkyl Iodides

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• 作者：Yangyang Shen ; Josep Cornella ; Francisco Juliá-Hernández ; Ruben Martin
• 刊名：ACS Catalysis
• 出版年：2017
• 出版时间：January 6, 2017
• 年：2017
• 卷：7
• 期：1
• 页码：409-412
• 全文大小：367K
• ISSN：2155-5435

文摘

A visible-light-mediated atom transfer radical cyclization of unactivated alkyl iodides is described. This protocol operates under mild conditions and exhibits high chemoselectivity profile while avoiding parasitic hydrogen atom transfer pathways. Preliminary mechanistic studies challenge the perception that a canonical photoredox catalytic cycle is being operative.