(R)-3,5-diCF3-SYNPHOS and (R)-p-CF3-SYNPHOS, Electron-Poor Diphosphines for Efficient Room Temperature Rh-Catalyzed Asymmetric Conjugate Addition of Arylboro

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• 作者：Farouk Berhal ; Olivier Esseiva ; Charles-Henri Martin ; Hitoshi Tone ; Jean-Pierre Genet ; Tahar Ayad ; Virginie Ratovelomanana-Vidal
• 刊名：Organic Letters
• 出版年：2011
• 出版时间：June 3, 2011
• 年：2011
• 卷：13
• 期：11
• 页码：2806-2809
• 全文大小：729K
• 年卷期：v.13,no.11(June 3, 2011)
• ISSN：1523-7052

文摘

Two new atropisomeric electron-poor chiral diphosphine ligand analogues of SYNPHOS were prepared, and their electronic properties are described. These two ligands afforded high performance for the Rh-catalyzed asymmetric 1,4-addition of arylboronic acids to 伪,尾-unsaturated carbonyl compounds at room temperature.