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Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2H)-ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors
详细信息
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作者:
Pei-Pei Kung
;
Eugene Rui
;
Simon Bergqvist
;
Patrick Bingham
;
John Braganza
;
Michael Collins
;
Mei Cui
;
Wade Diehl
;
Dac Dinh
;
Connie Fan
;
Valeria R. Fantin
;
Hovhannes J. Gukasyan
;
Wenyue Hu
;
Buwen Huang
;
Susan Kephart
;
Cody Krivacic
;
Robert A. Kumpf
;
Gary Li
;
Karen
A.
Maegley
;
Indrawan McAlpine
;
Lisa Nguyen
;
Sacha Ninkovic
;
Martha Ornelas
;
Michael Ryskin
;
Stephanie Scales
;
Scott Sutton
;
John Tatlock
;
Dominique Verhelle
;
Fen Wang
;
Peter Wells
;
Martin Wythes
;
Shinji Yamazaki
;
Brian Yip
;
Xiu Yu
;
Luke Zehnder
;
Wei-Guo Zhang
;
Robert A. Rollins
;
Martin Edwards
刊名:Journal of Medicinal Chemistry
出版年:2016
出版时间:September 22, 2016
年:2016
卷:59
期:18
页码:8306-8325
全文大小:785K
参考文献:
ISSN:1520-4804
文摘
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