Sila Morita-Baylis-Hillman Reaction of Cyclopropenes

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• 作者：Stepan Chuprakov ; Denis A. Malyshev ; Alexander Trofimov ; Vladimir Gevorgyan
• 刊名：Journal of the American Chemical Society
• 出版年：2007
• 出版时间：December 5, 2007
• 年：2007
• 卷：129
• 期：48
• 页码：14868 - 14869
• 全文大小：61K
• 年卷期：v.129,no.48(December 5, 2007)
• ISSN：1520-5126

文摘

The first example of sila-Morita-Bayis-Hillman reaction between 1-silylcyclopropenes and carbonyl compounds has been demonstrated. This novel phosphine-catalyzed transformation features a 1,3-Brook rearrangement/elimination cascade and provides convenient access to a variety of 1-(silyloxymethyl)cyclopropenes, which are not easily available via traditional methods.