Conversion from Arenes Having a Benzene Ring to Those Having a Picolinic Acid by Simple Growing Cell Reactions Using Escherichia coli that Expressed the Six Bacterial Genes Involv

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• 作者：Kazutoshi Shindo ; Ayako Osawa ; Ryoko Nakamura ; Yukiko Kagiyama ; Shohei Sakuda ; Yoshikazu Shizuri ; Kensuke Furukawa ; and Norihiko Misawa
• 刊名：Journal of the American Chemical Society
• 出版年：2004
• 出版时间：November 24, 2004
• 年：2004
• 卷：126
• 期：46
• 页码：15042 - 15043
• 全文大小：69K
• 年卷期：v.126,no.46(November 24, 2004)
• ISSN：1520-5126

文摘

The comprehensive bioconversion of aromatic compounds with a benzene ring to a picolinic acid was achieved with a recombinant Escherichia coli strain that expressed the six genes involved in biphenyl catabolism, these being the bphA1(2072)A2A3A4 genes encoding the evolved biphenyl dioxygenase, the bphB gene encoding dihydrodiol dehydrogenase, and the bphC gene encoding catechol 2,3-dioxygenase.