Wet Lab Accelerator: A Web-Based Application Democratizing Laboratory Automation for Synthetic Biology

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• 作者：Maxwell Bates ; Aaron J. Berliner ; Joe Lachoff ; Paul R. Jaschke ; Eli S. Groban
• 刊名：ACS Synthetic Biology
• 出版年：2017
• 出版时间：January 20, 2017
• 年：2017
• 卷：6
• 期：1
• 页码：167-171
• 全文大小：361K
• ISSN：2161-5063

文摘

Wet Lab Accelerator (WLA) is a cloud-based tool that allows a scientist to conduct biology via robotic control without the need for any programming knowledge. A drag and drop interface provides a convenient and user-friendly method of generating biological protocols. Graphically developed protocols are turned into programmatic instruction lists required to conduct experiments at the cloud laboratory Transcriptic. Prior to the development of WLA, biologists were required to write in a programming language called “Autoprotocol” in order to work with Transcriptic. WLA relies on a new abstraction layer we call “Omniprotocol” to convert the graphical experimental description into lower level Autoprotocol language, which then directs robots at Transcriptic. While WLA has only been tested at Transcriptic, the conversion of graphically laid out experimental steps into Autoprotocol is generic, allowing extension of WLA into other cloud laboratories in the future. WLA hopes to democratize biology by bringing automation to general biologists.