Regio- and Stereoselective Oxysulfonylation of Allenes

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• 作者：Zhiyuan Huang ; Qingquan Lu ; Yichang Liu ; Dong Liu ; Jian Zhang ; Aiwen Lei
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：August 19, 2016
• 年：2016
• 卷：18
• 期：16
• 页码：3940-3943
• 全文大小：319K
• 年卷期：0
• ISSN：1523-7052

文摘

A highly regio- and stereoselective oxysulfonylation of allenes was developed that provided direct access to 2-sulfonyl allylic alcohols in good yields. By means of dioxygen activation, selective difunctionlization of allenes could be successfully achieved under mild metal-free conditions. Preliminary mechanistic investigation disclosed that this transformation probably goes through a radical process.