Smartphone Operated Signal Transduction by Ion Nanogating (STING) Amplifier for Nanopore Sensors: Design and Analytical Application

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• 作者：Rıfat Emrah Özel ; Sina Kahnemouyi ; Hsinwen Fan ; Wai Han Mak ; Akshar Lohith ; Adam Seger ; Mircea Teodorescu ; Nader Pourmand
• 刊名：ACS Sensor
• 出版年：2016
• 出版时间：March 25, 2016
• 年：2016
• 卷：1
• 期：3
• 页码：265-271
• 全文大小：523K
• ISSN：2379-3694

文摘

In this report, we demonstrate a hand-held wireless voltage-clamp amplifier for current measurement of nanopore sensors. This amplifier interfaces a sensing probe and connects wirelessly with a computer or smartphone for the required stimulus input, data processing, and storage. To test the proposed signal transduction by ion nanogating (STING) wireless amplifier, in the current study the system was tested with a nano-pH sensor to measure pH of standard buffer solutions and the performance was compared against the commercial voltage-clamp amplifier. To the best of our knowledge, STING amplifier is the first miniaturized wireless voltage-clamp platform operated with a customized smartphone application (app).