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Lead Optimization toward Proof-of-Concept Tools for Huntington鈥檚 Disease within a 4-(1H-Pyrazol-4-yl)pyrimidine Class of Pan-JNK Inhibitors
详细信息
查看全文
作者:
John Wityak
;
Kevin F. McGee
;
Michael P. Conlon
;
Ren Hua Song
;
Bryan C. Duffy
;
Brent Clayton
;
Michael Lynch
;
Gwen Wang
;
Emily Freeman
;
James Haber
;
Douglas B. Kitchen
;
David D. Manning
;
Jiffry Ismail
;
Yuri Khmelnitsky
;
Peter Michels
;
Jeff Webster
;
Macarena Irigoyen
;
Michele Luche
;
Monica Hultman
;
Mei Bai
;
IokTeng D. Kuok
;
Ryan Newell
;
Marieke Lamers
;
Philip Leonard
;
Dawn Yates
;
Kim Matthews
;
Lynette Ongeri
;
Steve Clifton
;
Tania
Mead
;
Susan Deupree
;
Pat Wheelan
;
Kathy Lyons
;
Claire Wilson
;
Alex Kiselyov
;
Leticia Toledo-Sherman
;
Maria Beconi
;
Ignacio Mu帽oz-Sanjuan
;
Jonathan Bard
;
Celia Dominguez
刊名:Journal of Medicinal Chemistry
出版年:2015
出版时间:April 9, 2015
年:2015
卷:58
期:7
页码:2967-2987
全文大小:786K
ISSN:1520-4804
文摘
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