Monosubstituted Benzene Derivatives from Fruits of Ficus hirta and Their Antifungal Activity against Phytopathogen Penicillium italicum

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• 作者：Chunpeng Wan ; Jianxin Han ; Chuying Chen ; Liangliang Yao ; Jinyin Chen ; Tao Yuan
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：2016
• 出版时间：July 20, 2016
• 年：2016
• 卷：64
• 期：28
• 页码：5621-5624
• 全文大小：230K
• 年卷期：0
• ISSN：1520-5118

文摘

Ficus hirta, a widely consumed food by Hakka people, has been reported to show potent antifungal activity against phytopathogen Penicillium italicum. However, there is no report of chemical constituents responsible for the antifungal activity. In the current study, nine monosubstituted benzene derivatives, including three new derivatives (1–3), were isolated from the fruits of F. hirta. The structures of these isolates were elucidated on the basis of the analysis of spectroscopic data (mass spectrometry and nuclear magnetic resonance). All of the isolates were evaluated for antifungal activities against P. italicum. At an equivalent concentration, compound 1 exhibited stronger antifungal activity than that of the ethanol extract of F. hirta fruits.