Palladium-Catalyzed Direct Intramolecular C–N Bond Formation: Access to Multisubstituted Dihydropyrroles

详细信息    查看全文

• 作者：Bing Jiang ; Fei-Fan Meng ; Qiu-Ju Liang ; Yun-He XuTeck-Peng Loh
• 刊名：Organic Letters
• 出版年：2017
• 出版时间：February 17, 2017
• 年：2017
• 卷：19
• 期：4
• 页码：914-917
• 全文大小：459K
• ISSN：1523-7052

文摘

A palladium-catalyzed intramolecular amination of alkenes with retention of olefin functionalization was achieved under mild reaction conditions. In the presence of palladium catalyst, the tosyl-protected amine can directly couple with a double bond to provide versatile dihydropyrrole derivatives in moderate to excellent yields.