Asymmetric Synthesis of Planar Chiral Ferrocenes by Enantioselective Intramolecular C鈥揌 Arylation of N-(2-Haloaryl)ferrocenecarboxamides

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• 作者：Lantao Liu ; An-An Zhang ; Rui-Juan Zhao ; Feng Li ; Tuan-Jie Meng ; Naoki Ishida ; Masahiro Murakami ; Wen-Xian Zhao
• 刊名：Organic Letters
• 出版年：2014
• 出版时间：October 17, 2014
• 年：2014
• 卷：16
• 期：20
• 页码：5336-5338
• 全文大小：303K
• ISSN：1523-7052

文摘

The palladium-catalyzed intramolecular C鈥揌 arylation reaction of N-(2-bromoaryl)ferrocenecarboxamides furnishes planar chiral ferrocene derivatives. TADDOL-derived phosphoramide ligands induce enantioselectivities ranging from 91:9 to 98:2 er.