Inhibitors of Osteoclast Formation from Rhizomes of Cibotium barometz

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• 作者：Nguyen Xuan Cuong ; Chau Van Minh ; Phan Van Kiem ; Hoang Thanh Huong ; Ninh Khac Ban ; Nguyen Xuan Nhiem ; Nguyen Huu Tung ; Ji-Won Jung ; Hyun-Ju Kim ; Shin-Yoon Kim ; Jeong Ah Kim ; Young Ho Kim
• 刊名：Journal of Natural Products
• 出版年：2009
• 出版时间：September 25, 2009
• 年：2009
• 卷：72
• 期：9
• 页码：1673-1677
• 全文大小：242K
• 年卷期：v.72,no.9(September 25, 2009)
• ISSN：1520-6025

文摘

Eight compounds (1−8) were isolated from a methanol extract of Cibotium barometz rhizomes including two new furan derivatives, cibotiumbarosides A (1) and B (2), and a new glycoglycerolipid, cibotiglycerol (4). Their structures were elucidated by chemical and spectroscopic methods. Compounds 2−5 each showed inhibition of osteoclast formation with no affect on BMM cell viability.