Effect of Selenium Supplementation on Lipid Peroxidation, Antioxidant Enzymes, and Lactate Levels in Rats Immediately After Acute Swimming Exercise

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• 作者：Mustafa Akil (1)
  Umit Gurbuz (2)
  Mursel Bicer (3)
  Abdullah Sivrikaya (4)
  Rasim Mogulkoc (5)
  Abdulkerim Kasim Baltaci (6)
  
• 关键词：Selenium ; Exercise ; Free radicals ; Antioxidant activity ; Lactate
• 刊名：Biological Trace Element Research
• 出版年：2011
• 出版时间：September 2011
• 年：2011
• 卷：142
• 期：3
• 页码：651-659
• 全文大小：137KB
• 参考文献：1. Brown KM, Arthur JR (2001) Selenium selenoproteins and human healt: a review. Public Health Nutr 4:593-99 CrossRef
  2. Olivieri O, Negri M, De Gironcoli M, Bassi A, Guarini P, Stanzial AM, Grigolini L, Ferrari S, Corrocher R et al (1988) Effects of dietary fish oil on malondialdehyde production and glutathione peroxidase activity in hyperlipidaemic patients. Scand J Clin Lab Invest 48:659-65
  3. Holben DH, Smith AM (1999) The diverse role of selenium within selenoproteins: a review. J Am Diet Assoc 99:836-43 CrossRef
  4. Sen CK, Packer L (2000) Thiol homeostasis and supplements in physical exercise. J Am Clin Nutr 72:653-69
  5. Ji LL, Stratman FW, Lardy HA (1988) Antioxidant enzyme systems in rat liver and skeletal muscle. Influences of selenium deficiency, chronic training, and acute exercise. Arch Biochem Biophys 263:150-60 CrossRef
  6. Zamora AJ, Tessier F, Marconnet P, Margaritis I, Marini JF (1995) Mitochondria changes in human muscle after prolonged exercise, endurance training and selenium supplementation. Eur J Appl Physiol Occup Physiol 71:505-11 CrossRef
  7. Margaritis I, Tessier F, Prou E, Marconnet P, Marini JF (1997) Effects of endurance training on skeletal muscle oxidative capacities with and without selenium supplementation. J Trace Elem Med Biol 11:37-3
  8. Tessier F, Margaritis I, Richard MJ, Moynot C, Marconnet P (1995) Selenium and training effects on the glutathione system and aerobic performance. Med Sci Sports Exerc 27:390-96
  9. Thomson CD (2004) Assessment of requirements for selenium and adequacy of selenium status: a review. Eur J Clin Nutr 58:391-02 CrossRef
  10. Clarkson PM (1995) Antioxidants and physical performance. Crit Rev Food Sci Nutr 35:131-41 CrossRef
  11. Jana K, Samanta PK, Manna I, Ghosh P, Singh N, Khetan RP, Ray BR (2008) Protective effect of sodium selenite and zinc sulfate on intensive swimming-induced testicular gamatogenic and steroidogenic disorders in mature male rats. Appl Physiol Nutr Metab 33:903-14 CrossRef
  12. Draper HH, Hadley M (1990) Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol 186:421-31 CrossRef
  13. Atroshi F, Sankari S, Osterberg S, Sandholm M (1981) Variation of erythrocyte glutathione peroxidase activity in Finn sheep. Res Vet Sci 31:267-71
  14. Michailidis Y, Jamurtas AZ, Nikolaidis MG, Fatouros IG, Koutedakis Y, Papassotiriou I, Kouretas D (2007) Sampling time is crucial for measurement of aerobic exercise-induced oxidative stress. Med Sci Sports Exerc 39:1107-113 CrossRef
  15. Maughan RJ, Donnelly AE, Gleeson M, Whiting PH, Walker KA, Clough PJ (1989) Delayed-onset muscle damage and lipid peroxidation in man after a downhill run. Muscle Nerve 12:332-36 CrossRef
  16. Vollaard NB, Shearman JP, Cooper CE (2005) Exercise-induced oxidative stress: myths, realities and physiological relevance. Sports Med 35:1045-062 CrossRef
  17. Davison GW, Hughes CM, Bell RA (2005) Exercise and mononuclear cell DNA damage: the effects of antioxidant supplementation. Int J Sport Nutr Exerc Metab 15:480-92
  18. Goldfarb AH, McIntosh MK, Boyer BT (1996) Vitamin E attenuates myocardial oxidative stress induced by DHEA in rested and exercised rats. J Appl Physiol 80:486-90
  19. Reddy KV, Kumar TC, Prasad M, Reddanna P (1998) Pulmonary lipid peroxidation and antioxidant defenses during exhaustive physical exercise: the role of vitamin E and selenium. Nutrition 14:448-51 CrossRef
  20. Ji LL, Stratman FW, Lardy HA (1992) Antioxidant enzyme response to selenium deficiency in rat myocardium. J Am Coll Nutr 11:79-6
  21. Veera Reddy K, Charles Kumar T, Prasad M, Reddanna P (1992) Exercise-induced oxidant stress in the lung tissue: role of dietary supplementation of vitamin E and selenium. Biochem Int 26:863-71
  22. Hagobian TA, Jacobs KA, Subudhi AW, Fattor JA, Rock PB, Muza SR, Fulco CS, Braun B, Grediagin A, Mazzeo RS, Cymerman A, Friedlander AL (2006) Cytokine responses at high altitude: effects of exercise and antioxidants at 4300?mt. Med Sci Sports Exerc 38:276-85 CrossRef
  23. Emre MH, Duzova H, Sancak B, Polat A, Erdogan H, Yologlu S (2004) Serum selenium response to maximal anaerobic exercise among sportsmen trained at various levels. J Trace Elem Exp Med 17:93-00 CrossRef
  24. Ortenblad N, Madsen K, Djurhuus MS (1997) Antioxidant status and lipid peroxidation after shortterm maximal exercise in trained and untrained humans. Am J Physiol 272:1258-263
  25. Tiidus PM (1998) Radical species in inflammation and overtraining. Can J Physiol Pharmacol 76:533-38 CrossRef
  26. Helwig B (2000) Selenium. Antioxidants and Exercise. Graduate thesis (under the supervision of Dr. Katherine Grunewald). Graduate of the Department of Human Nutrition 4, Kansas State University, Kansas
  27. Powers SK, Ji LL, Leeuwenburgh C (1999) Exercise training-induced alterations in skeletal muscle antioxidant capacity: a brief review. Med Sci Sports Exerc 31:987-97 CrossRef
  28. Kim HT (2005) Effect of the joint administration of selenium and vitamin E in combination with regular aerobic exercise on markers of lipid peroxidation and glutathione peroxidase in diabetic rats. Int J Sport Nutr Exerc Metab 15:266-78
  29. Tessier F, Hida H, Favier A, Marconnet P (1995) Muscle GSH-Px activity after prolonged exercise, training, and selenium supplementation. Biol Trace Elem Res 47:279-85 CrossRef
  30. Kirschvink N, De Moffarts B, Farnir F, Pincemail J, Lekeux P (2006) Investigation of blood oxidant/antioxidant markers in healthy competition horses of different breeds. Equine Vet J Suppl 36:239-44 CrossRef
  31. Ohno H, Yahata T, Sato Y, Yamamura K, Taniguchi N (1988) Physical training and fasting erythrocyte activities of free radical scavenging enzyme systems in sedentary men. Eur J Appl Physiol Occup Physiol 57:173-76 CrossRef
  32. Leeuwenburg C, Fiebig R, Chandvaney R, Ji LL (1994) Aging and exercise training in skeletal muscle: responses of glutathione and antioxidant enzyme systems. Am J Physiol 267:439-45
  33. Hornberger TA, McLoughlin TJ, Leszczynski JK, Armstrong DD, Jameson RR, Bowen PE, Hwang ES, Hou H, Moustafa ME, Carlson BA, Hatfield DL, Diamond AM, Esser KA (2003) Selenoprotein-deficient transgenic mice exhibit enhanced exercise-induced muscle growth. J Nutr 133:3091-097
  34. Powers SK, Criswell D, Lawler J, Ji LL, Martin D, Herb RA, Dudley G (1994) Influence of exercise and fiber type on antioxidant enzyme activity in rat skeletal muscle. Am J Physiol 266:375-80
  35. Rousseau AS, Margaritis I, Arnaud J, Faure H, Roussel AM (2006) Physical activity alters antioxidant status in exercising elderly subjects. J Nutr Biochem 17:463-70 CrossRef
  36. Grant S, McMillan K, Newell J, Wood L, Keatley S, Simpson D, Leslie K, Fairlie-Clark S (2002) Reproducibility of the blood lactate threshold, 4?mmol.l(-) marker, heart rate and ratings of perceived exertion during incremental treadmill exercise in humans. Eur J Appl Physiol 87:159-66 CrossRef
  37. Rodas G, Ventura JL, Cadefau JA, Cusso R, Parra J (2000) A short training programme for the rapid improvement of both aerobic and anaerobic metabolism. Eur J Appl Physiol 82:480-86 CrossRef
  38. Mills CF (1970) Trace elements metabolism in animals. In: Proceedings of WAAP/IBP International Symposium, London. pp. 339-43
  39. Milias GA, Nomikos T, Fragopoulou E, Athanasopoulos S, Antonopoulou S (2006) Effects of baseline serum levels of Se on markers of eccentric exercise-induced muscle injury. Biofactors 26:161-70 CrossRef
  40. Kaczmarski M, Wójcicki J, Samochowiec L, Dutkiewicz T, Sych Z (1999) The influence of exogenous antioxidants and physical exercise on some parameters associated with production and removal of free radicals. Pharmazie 54:303-06
  
• 作者单位：Mustafa Akil (1)
  Umit Gurbuz (2)
  Mursel Bicer (3)
  Abdullah Sivrikaya (4)
  Rasim Mogulkoc (5)
  Abdulkerim Kasim Baltaci (6)
  
  1. City Office of Youth Sport, 42040, Konya, Turkey
  2. School of Veterinary, Department of Food Hygene, Selcuk University, Konya, Turkey
  3. School of Physical Education and Sports, Sel?uk University, Konya, Turkey
  4. Selcuklu School of Medicine, Department of Biochemistry, Sel?uk University, Konya, Turkey
  5. Meram School of Medicine, Department of Physiology, Sel?uk University, Konya, Turkey
  6. Selcuklu School of Medicine, Department of Physiology, Sel?uk University, Konya, Turkey
  

文摘

The present study aims to evaluate the effect of selenium supplementation on lipid peroxidation and lactate levels in rats subjected to acute swimming exercise. Thirty-two adult male rats of Sprague–Dawley type were divided into four groups. Group 1, control; group 2, selenium-supplemented; group 3, swimming control; group 4, selenium-supplemented swimming group. The animals in groups 2 and 4 were supplemented with (i.p.) 6?mg/kg/day sodium selenite for 4?weeks. The blood samples taken from the animals by decapitation method were analyzed in terms of erythrocyte-reduced glutathione (GSH), serum glutathione peroxidase (GPx) and superoxide dismutase (SOD), and plasma malondialdehyde (MDA) and lactate using the colorimetric method, and serum selenium values using an atomic emission device. In the study, the highest MDA and lactate values were found in group 3, while the highest GSH, GPx and SOD values were obtained in group 4 (p-lt;-,001). Group 2 had the highest and group 3 had the lowest selenium levels (p-lt;-,001). Results of the study indicate that the increase in free radical production and lactate levels due to acute swimming exercise in rats might be offset by selenium supplementation. Selenium supplementation may be important in that it supports the antioxidant system in physical activity.