Apparent diffusion coefficient mapping in medulloblastoma predicts non-infiltrative surgical planes

详细信息    查看全文

• 作者：Neena I. Marupudi ; Deniz Altinok ; Luis Goncalves ; Steven D. Ham…
• 关键词：Medulloblastoma ; Apparent diffusion coefficient map ; Diffusion ; weighted imaging ; ADC map ; Surgical planes
• 刊名：Child's Nervous System
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：32
• 期：11
• 页码：2183-2187
• 全文大小：768 KB
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Neurosurgery
  Neurosciences
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1433-0350
• 卷排序：32

文摘

IntroductionAn appropriate surgical approach for posterior fossa lesions is to start tumor removal from areas with a defined plane to where tumor is infiltrating the brainstem or peduncles. This surgical approach minimizes risk of damage to eloquent areas. Although magnetic resonance imaging (MRI) is the current standard preoperative imaging obtained for diagnosis and surgical planning of pediatric posterior fossa tumors, it offers limited information on the infiltrative planes between tumor and normal structures in patients with medulloblastomas. Because medulloblastomas demonstrate diffusion restriction on apparent diffusion coefficient map (ADC map) sequences, we investigated the role of ADC map in predicting infiltrative and non-infiltrative planes along the brain stem and/or cerebellar peduncles by medulloblastomas prior to surgery.