Successful treatment of aortic root dilatation in a patient with relapsing polychondritis

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• 作者：Aman Sharma (1)
  Tarun Mittal (1)
  Susheel Kumar (1)
  Arjun Datt Law (1)
  Ajay Wanchu (1)
  Rajiv Mahajan (2)
  Pradeep Bambery (3)
  Surjit Singh (1)
  
• 关键词：Aortic insufficiency ; Cardiac involvement ; Immunosupression ; Relapsing polychondritis
• 刊名：Clinical Rheumatology
• 出版年：2013
• 出版时间：March 2013
• 年：2013
• 卷：32
• 期：1/suppl
• 页码：59-61
• 全文大小：139KB
• 参考文献：1. Sharma A, Bambery P, Wanchu A, Sharma YP, Panda N, Gupta AK, Singh S (2007) Relapsing polychondritis in North India: a report of ten patients. Scand J Rheumatol 36:462-65 CrossRef
  2. McAdam LP, O'Hanlan MA, Bluestone R, Pearson CM (1976) Relapsing polychondritis: prospective study of 23 patients and a review of the literature. Medicine (Baltimore) 55:193-13 CrossRef
  3. Rho YH, Choi SJ, Lee YH, Song GG (2005) Relapsing polychondritis with aortitis without valvular involvement. J Rheumatol 32:954-56
  4. Damiani JM, Levine HL (1979) Relapsing polychondritis—report of 10 cases. Laryngoscope 89:929-46 CrossRef
  5. Marshall DS, Jackson R, Rae AP, Capell HA (1992) Early aortic valve cusp rupture in relapsing polychondritis. Ann Rheum Dis 51:413-15 CrossRef
  6. Walker UA, Weiner SM, Vaith MU et al (1998) Aortitis in relapsing polychondritis. British J Rheumatology 37:1359-361 CrossRef
  7. Marie I, Lahaxe L, Josse S et al (2009) Sustained response to infliximab in a patient with relapsing polychondritis with aortic involvement. Rheumatol 48:1328-329 CrossRef
  8. Seymour MW, Home DM, Williams RO et al (2007) Prolonged response to anti-tumour necrosis factor treatment with adalimumab (Humira) in relapsing polychondritis complicated by aortitis. Rheumatology 46:1738-739 CrossRef
  9. Selim AG, Fulford LG, Mohiaddin RH, Sheppard MN (2001) Active aortitis in relapsing polychondritis. J Clin Pathol 54:890-92 CrossRef
  
• 作者单位：Aman Sharma (1)
  Tarun Mittal (1)
  Susheel Kumar (1)
  Arjun Datt Law (1)
  Ajay Wanchu (1)
  Rajiv Mahajan (2)
  Pradeep Bambery (3)
  Surjit Singh (1)
  
  1. Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, 160012, Chandigarh, India
  2. Department of Cardiology, Postgraduate Institute of Medical Education and Research, 160012, Chandigarh, India
  3. Bundaberg Base Hospital, Bundaberg, Australia
  
• ISSN：1434-9949

文摘

Cardiovascular involvement occurring in 20-0% patients is the second most common cause of mortality in patients with relapsing polychondritis. Aortic insufficiency occurs as a result of aortic root dilatation rather than primary valvular involvement. We are reporting a patient of relapsing polychondritis with aortic root dilatation, in whom institution of early and aggressive therapy successfully prevented the progression of aortic insufficiency.