Glycosyltransferases: key players involved in the modification of plant secondary metabolites

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• 作者：Jun Wang (1)
  Bingkai Hou (1)
  
• 关键词：glycosyltransferases ; glycosylation ; plant secondary metabolite ; metabolic engineering
• 刊名：Frontiers in Biology
• 出版年：2009
• 出版时间：March 2009
• 年：2009
• 卷：4
• 期：1
• 页码：39-46
• 全文大小：134KB
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• 作者单位：Jun Wang (1)
  Bingkai Hou (1)
  
  1. The key Laboratory of Plant Cell Engineering and Germplasm Innovation, Ministry of Education, and School of Life Science, Shandong University, Jinan, 250100, China
  
• ISSN：1674-7992

文摘

Glycosyltransferases are members of the multigene superfamily in plants that can transfer single or multiple activated sugars to a range of plant molecules, resulting in the glycosylation of plant compounds. Although the activities of many glycosyltransferases and their products have been recognized for a long time, only in recent years were some glycosyltransferase genes identified and a few functionally characterized in detail. Glycosylation is thought to be one of the most important modification reactions towards plant secondary metabolites, and plays a key role in maintaining cell homeostasis, thus likely participating in the regulation of plant growth, development and in defense responses to stress environments. With advances in plant genome projects and the development of novel technologies in analyzing gene function, significant progress could be made in gaining new insights into the properties and precise biological roles of plant secondary product glycosyltransferases, and the new knowledge will have extensive application prospects in the catalytic synthesis of glycoconjugates and metabolic engineering of crops. In this review, we summarize the current research, highlighting the possible biological roles, of plant secondary metabolite glycosyltransferases and discuss their potential applications as well as aspects to be further studied in the near future.