Age-related differences in anxiety-like behavior and amygdalar CCL2 responsiveness to stress following alcohol withdrawal in male Wistar rats

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• 作者：Kathryn M Harper ; Darin J Knapp ; Meredith A. Park ; George R Breese
• 关键词：Ethanol ; Neurons ; Astrocytes ; Microglia ; Adolescent ; Adult
• 刊名：Psychopharmacology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：234
• 期：1
• 页码：79-88
• 全文大小：
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Neurosciences; Pharmacology/Toxicology; Psychiatry;
• 出版者：Springer Berlin Heidelberg
• ISSN：1432-2072
• 卷排序：234

文摘

RationaleBehavioral and neuroimmune vulnerability to withdrawal from chronic alcohol varies with age. The relation of anxiety-like behavior to amygdalar CCL2 responses following stress after withdrawal from chronic intermittent alcohol (CIA) was investigated in adolescent and adult rats.