Intrathecal Th17- and B cell-associated cytokine and chemokine responses in relation to clinical outcome in Lyme neuroborreliosis: a large retrospective study

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Intrathecal Th17- and B cell-associated cytokine and chemokine responses in relation to clinical outcome in Lyme neuroborreliosis: a large retrospective study

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作者：Paula Gyllemark ; Pia Forsberg ; Jan Ernerudh…
关键词：Lyme neuroborreliosis ; Cerebrospinal fluid ; Cytokines ; Chemokines ; APRIL ; BAFF ; CCL20 ; CXCL 1 ; CXCL13 ; IL ; 17A
刊名：Journal of Neuroinflammation
出版年：2017
出版时间：December 2017
年：2017
卷：14
期：1
全文大小：669KB
刊物主题：Neurosciences; Neurology; Neurobiology; Immunology;
出版者：BioMed Central
ISSN：1742-2094
卷排序：14

文摘

BackgroundB cell immunity, including the chemokine CXCL13, has an established role in Lyme neuroborreliosis, and also, T helper (Th) 17 immunity, including IL-17A, has recently been implicated.