Epidemiology of venous thromboembolism in patients with liver diseases: a systematic review and meta-analysis

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• 作者：Xingshun Qi (1) (2)
  Weirong Ren (2) (3)
  Xiaozhong Guo (1)
  Daiming Fan (2)
  
  1. Department of Gastroenterology ; General Hospital of Shenyang Military Area ; No. 83 Wehua Road ; Shenyang ; 110840 ; China
  2. Xijing Hospital of Digestive Diseases ; Fourth Military Medical University ; No. 127 Changle West Road ; Xi鈥檃n ; 710032 ; China
  3. Department of Digestive Diseases ; Sanmenxia Central Hospital ; Henan University of Science and Technology ; Xiaoshan Road ; Sanmenxia ; 472000 ; China
  
• 关键词：Deep vein thrombosis ; Pulmonary embolism ; Prevalence ; Incidence ; Liver cirrhosis
• 刊名：Internal and Emergency Medicine
• 出版年：2015
• 出版时间：March 2015
• 年：2015
• 卷：10
• 期：2
• 页码：205-217
• 全文大小：603 KB
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• 刊物主题：Internal Medicine;
• 出版者：Springer Milan
• ISSN：1970-9366

文摘

The risk of venous thromboembolism (VTE) may be increased in patients with liver diseases. A systematic review and meta-analysis were conducted to analyze the epidemiology of VTE in such patients. All relevant studies were searched via the PubMed, EMBASE, and Cochrane Library databases. The incidence and prevalence of VTE were pooled using random-effect models. Subgroup analyses were conducted according to the type of VTE [deep vein thrombosis (DVT), pulmonary embolism (PE)], type of liver disease (liver cirrhosis alone/unclassified liver diseases or non-cirrhotics), region in which the study was performed (USA/Europe/Asia), number of total observed patients with liver diseases (>1,000/