Improvement of overall survival in stage IV melanoma patients during 2011–2014: analysis of real-world data in 441 patients of the German Central Malignant Melanoma Registry (CMMR)

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• 作者：Andrea Forschner ; Felizitas Eichner…
• 关键词：Melanoma ; Survival ; Checkpoint inhibitors ; Targeted therapy ; Chemotherapy ; Pembrolizumab ; Nivolumab ; Ipilimumab ; Brain metastasis
• 刊名：Journal of Cancer Research and Clinical Oncology
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：143
• 期：3
• 页码：533-540
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Oncology; Cancer Research; Internal Medicine; Hematology;
• 出版者：Springer Berlin Heidelberg
• ISSN：1432-1335
• 卷排序：143

文摘

BackgroundDuring 2011 and 2014, new treatment modalities like tyrosine kinase inhibitors and checkpoint inhibitors were introduced into the therapy of metastatic melanoma. This study addresses the question whether overall survival (OS) of metastatic melanoma patients has already been improved in 441 patients diagnosed with metastatic melanoma between 2011 and 2014 in the real-world setting at the University Hospital Tuebingen.