Sex-specific chromatin landscapes in an ultra-compact chordate genome

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• 作者：Pavla Navratilova ; Gemma Barbara Danks ; Abby Long…
• 关键词：Histone ; Enhancer ; Spermatogenesis ; Polycomb ; Dosage compensation ; Heterochromatin ; Transposable elements ; Endocycle
• 刊名：Epigenetics & Chromatin
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：10
• 期：1
• 全文大小：5601KB
• 刊物主题：Animal Genetics and Genomics; Human Genetics; Plant Genetics & Genomics; Cell Biology; Gene Expression; Gene Function;
• 出版者：BioMed Central
• ISSN：1756-8935
• 卷排序：10

文摘

BackgroundIn multicellular organisms, epigenome dynamics are associated with transitions in the cell cycle, development, germline specification, gametogenesis and inheritance. Evolutionarily, regulatory space has increased in complex metazoans to accommodate these functions. In tunicates, the sister lineage to vertebrates, we examine epigenome adaptations to strong secondary genome compaction, sex chromosome evolution and cell cycle modes.