Negative serology: could exclude the diagnosis of brucellosis?

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• 作者：Aygul Dogan ?elik (1)
  Zerrin Yulugkural (1)
  Cumhur Kilincer (2)
  Mustafa Kemal Hamamcioglu (2)
  Figen Kuloglu (1)
  Filiz Akata (1)
  
• 关键词：Seronegative ; Brucellosis ; Spondylodiscitis
• 刊名：Rheumatology International
• 出版年：2012
• 出版时间：August 2012
• 年：2012
• 卷：32
• 期：8
• 页码：2547-2549
• 全文大小：317KB
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• 作者单位：Aygul Dogan ?elik (1)
  Zerrin Yulugkural (1)
  Cumhur Kilincer (2)
  Mustafa Kemal Hamamcioglu (2)
  Figen Kuloglu (1)
  Filiz Akata (1)
  
  1. Infectious Diseases Department, Trakya University Medical Faculty, Edirne, Turkey
  2. Neurosurgery Department, Trakya University Medical Faculty, Edirne, Turkey
  

文摘

Two cases of brucellar spondylodiscitis of the lumbar area were presented. Although both cases showed typical radiological changes, serological tests could not detect Brucella agglutinating antibodies. One of the patients was bacteremic and Brucella spp. was identified from blood culture. In the second patient needle biopsy was required for definite diagnosis. Although small, serologic tests have a certain rate of false negative results in brucellosis. Thus, a negative serology should not exclude the diagnosis of brucellosis, as it is demonstrated in the current cases.