A dual substrate kinetic model for cytochrome P450<sub class="a-plus-plus">BM3</sub>-F87G catalysis: simultaneous binding of long chain aldehydes and 4-fluorophenol

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A dual substrate kinetic model for cytochrome P450_BM3-F87G catalysis: simultaneous binding of long chain aldehydes and 4-fluorophenol

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作者：Chelsea Ledford ; Monica McMahon ; Ashley Whitesell ; Ghalib Khan…
关键词：Active site ; Aldehydes ; Benzoquinone ; Cytochrome P450 ; De ; fluorination ; 4 ; Fluorophenol
刊名：Biotechnology Letters
出版年：2017
出版时间：February 2017
年：2017
卷：39
期：2
页码：311-321
全文大小：
刊物类别：Biomedical and Life Sciences
刊物主题：Microbiology; Biotechnology; Applied Microbiology; Biochemistry, general;
出版者：Springer Netherlands
ISSN：1573-6776
卷排序：39

文摘

ObjectiveTo develop a model for binding and catalysis associated with the stimulation of 4-fluorophenol (4-FP) oxidation in the presence of long chain aldehydes by the enzymatic catalyst, cytochrome P450_BM3-F87G.