Chronically Recurrent and Widespread Tinea Corporis Due to Trichophyton rubrum in an Immunocompetent Patient

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• 作者：Q. T. Kong (1)
  X. Du (1)
  R. Yang (1)
  S. Y. Huang (1)
  H. Sang (1)
  W. D. Liu (2)
  
  1. Jinling Hospital ; Department of Dermatology ; Nanjing University ; School of Medicine ; Nanjing ; 210002 ; People鈥檚 Republic of China
  2. Institute of Dermatology ; Chinese Academy of Medical Sciences ; Peking Union Medical College ; Nanjing ; 210042 ; People鈥檚 Republic of China
  
• 关键词：Chronically ; Widespread ; Tinea corporis ; Trichophyton rubrum ; Immunocompetent
• 刊名：Mycopathologia
• 出版年：2015
• 出版时间：April 2015
• 年：2015
• 卷：179
• 期：3-4
• 页码：293-297
• 全文大小：1,089 KB
• 参考文献：1. Jackson, CJ, Barton, RC, Kelly, SL, Evans, EG (2000) Strain identification of Trichophyton rubrum by specific amplification of subrepeat elements in the ribosomal DNA nontranscribed spacer. J Clin Microbiol 38: pp. 4527-4534
  2. Gorani, A, Schiera, A, Oriani, A (2002) Case report. Widespread tinea corporis due to Trichophyton rubrum. Mycoses 45: pp. 195-197 CrossRef
  3. Vittorio, CC (1997) Widespread tinea corporis in an immunocompetent patient resistant to all conventional forms of treatment. Cutis 60: pp. 283-285
  4. Balci, DD, Cetin, M (2008) Widespread, chronic, and fluconazole-resistant Trichophyton rubrum infection in an immunocompetent patient. Mycoses 51: pp. 546-548 CrossRef
  5. Almeida, SR (2008) Immunology of dermatophytosis. Mycopathologia 166: pp. 277-283 CrossRef
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Life Sciences
  Microbiology
  Medical Microbiology
  Plant Sciences
  Microbial Ecology
  
• 出版者：Springer Netherlands
• ISSN：1573-0832

文摘

A 31-year-old immunocompetent male who presented with a 4-year history of extensive erythematous and scaly plaques involving the abdomen, gluteal and inguen regions with concomitant tinea pedis and onychomycosis is described. Diagnosis was based on positive mycological examination and positive histopathologic examination. Species identification was performed by growth on Sabouraud dextrose agar and by sequencing of the internal transcribed spacer regions of the rDNA region. The pathogen identified was Trichophyton rubrum. The same fungal species was cultured from his abdominal, gluteal, foot and toenail. A combination therapy with systemic terbinafine and topically applied terbinafine cream was successful. A 1-year follow-up did not show any recurrence of infection.