A genome-wide association study in a large F2-cross of laying hens reveals novel genomic regions associated with feather pecking and aggressive pecking behavior

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• 作者：Vanessa Lutz ; Patrick Stratz ; Siegfried Preuß ; Jens Tetens…
• 刊名：Genetics Selection Evolution
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：49
• 期：1
• 全文大小：2339KB
• 刊物主题：Animal Genetics and Genomics; Evolutionary Biology; Agriculture;
• 出版者：BioMed Central
• ISSN：1297-9686
• 卷排序：49

文摘

BackgroundFeather pecking and aggressive pecking in laying hens are serious economic and welfare issues. In spite of extensive research on feather pecking during the last decades, the motivation for this behavior is still not clear. A small to moderate heritability has frequently been reported for these traits. Recently, we identified several single-nucleotide polymorphisms (SNPs) associated with feather pecking by mapping selection signatures in two divergent feather pecking lines. Here, we performed a genome-wide association analysis (GWAS) for feather pecking and aggressive pecking behavior, then combined the results with those from the recent selection signature experiment, and linked them to those obtained from a differential gene expression study.