BFPTool: a software tool for analysis of Biomembrane Force Probe experiments

详细信息    查看全文

• 作者：Daniel Šmít ; Coralie Fouquet ; Mohamed Doulazmi ; Frédéric Pincet…
• 关键词：Biomembrane Force Probe ; Motion tracking ; Image analysis ; Force spectroscopy ; Cell mechanics
• 刊名：BMC Biophysics
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：10
• 期：1
• 全文大小：1175KB
• 刊物主题：Biological and Medical Physics, Biophysics; Life Sciences, general; Biological Techniques;
• 出版者：BioMed Central
• ISSN：2046-1682
• 卷排序：10

文摘

BackgroundThe Biomembrane Force Probe is an approachable experimental technique commonly used for single-molecule force spectroscopy and experiments on biological interfaces. The technique operates in the range of forces from 0.1 pN to 1000 pN. Experiments are typically repeated many times, conditions are often not optimal, the captured video can be unstable and lose focus; this makes efficient analysis challenging, while out-of-the-box non-proprietary solutions are not freely available.