An Update on Kaposi’s Sarcoma: Epidemiology, Pathogenesis and Treatment

详细信息    查看全文

• 作者：Paul Curtiss ; Lauren C. Strazzulla ; Alvin E. Friedman-Kien
• 关键词：Acquired immunodeficiency syndrome ; Human immunodeficiency virus ; Immunosuppression ; Kaposi’s sarcoma
• 刊名：Dermatology and Therapy
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：6
• 期：4
• 页码：465-470
• 全文大小：394KB
• 刊物主题：Internal Medicine; Dermatology; Plastic Surgery; Oral and Maxillofacial Surgery; Quality of Life Research;
• 出版者：Springer Healthcare
• ISSN：2190-9172
• 卷排序：6

文摘

Kaposi’s sarcoma is an angioproliferative neoplasm which has undergone considerable epidemiologic change since the original description by Moritz Kaposi in the late 1800s. This opportunistic neoplasm gained widespread notoriety within the US during the height of the AIDS epidemic, where it was frequently found co-occurring with opportunistic infections. With the advent of modern antiretroviral therapies, as well as an increasing number of individuals on immunosuppression for autoimmune disease or organ transplantation, the landscape of the immunocompromised individual has changed. It is now important for clinicians to be mindful of Kaposi’s sarcoma manifesting in a growing variety of clinical contexts.