The protective role of autophagy in experimental osteoarthritis, and the therapeutic effects of Torin 1 on osteoarthritis by activating autophagy

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• 作者：Ni-Tao Cheng ; Ai Guo ; Hai Meng
• 关键词：Autophagy ; Osteoarthritis ; Cartilage degeneration ; Torin 1 ; Protective role
• 刊名：BMC Musculoskeletal Disorders
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：17
• 期：1
• 全文大小：2,422 KB
• 刊物主题：Orthopedics; Rehabilitation; Rheumatology; Sports Medicine; Internal Medicine;
• 出版者：BioMed Central
• ISSN：1471-2474

文摘

Background Recent studies have shown that autophagy was associated with the development of osteoarthritis (OA), the purpose of this research was to determine the exact role of autophagy in OA and investigate effective therapeutic drugs to inhibit the pathological progression of OA.