Pretreatments with injured microenvironmental signals altered the characteristics of human umbilical cord mesenchymal stem cells

详细信息    查看全文

• 作者：Huiling Cao ; Qian Hui ; Yongmin Yan ; Chunbing Zhang ; Xuewen Yang…
• 关键词：Hepatocyte growth factor ; Insulin growth factor ; Kidney injury ; Mesenchymal stem cells ; Pretreatment ; Stem cell therapy ; Umbilical cord stem cells
• 刊名：Biotechnology Letters
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：38
• 期：1
• 页码：157-165
• 全文大小：2,070 KB
• 参考文献：Abd-Allah SH, Shalaby SM, El-Shal AS et al (2014) Effect of bone marrow-derived mesenchymal stromal cells on hepatoma. Cytotherapy 16:1197–1206PubMed CrossRef
  Batchelder CA, Lee CC, Martinez ML et al (2010) Ontogeny of the kidney and renal developmental markers in the rhesus monkey (Macaca mulatta). Anat Rec (Hoboken) 293:1971–1983CrossRef
  Cao H, Xu W, Qian H et al (2009) Mesenchymal stem cell-like cells derived from human gastric cancer tissues. Cancer Lett 274:61–71PubMed CrossRef
  Cao H, Qian H, Xu W et al (2010) Mesenchymal stem cells derived from human umbilical cord ameliorate ischemia/reperfusion-induced acute renal failure in rats. Biotechnol Lett 32:725–732PubMed CrossRef
  Cui Y, Sun YW, Lin HS et al (2014) Platelet-derived growth factor-BB induces matrix metalloproteinase-2 expression and rat vascular smooth muscle cell migration via ROCK and ERK/p38 MAPK pathways. Mol Cell Biochem 393:255–263PubMed CrossRef
  Eisel F, Boosen M, Beck M et al (2013) Platelet-derived growth factor triggers PKA-mediated signalling by a redox-dependent mechanism in rat renal mesangial cells. Biochem Pharmacol 85:101–108PubMed CrossRef
  Galie PA, Stegemann JP (2014) Injection of mesenchymal stromal cells into a mechanically stimulated in vitro model of cardiac fibrosis has paracrine effects on resident fibroblasts. Cytotherapy 16:906–914PubMed PubMedCentral CrossRef
  Liu H, Liu S, Li Y et al (2012) The role of SDF-1-CXCR4/CXCR7 axis in the therapeutic effects of hypoxia-preconditioned mesenchymal stem cells for renal ischemia/reperfusion injury. PLoS One 7:e34608PubMed PubMedCentral CrossRef
  Sabapathy V, Sundaram B, MS V et al (2014) Human Wharton’s Jelly Mesenchymal Stem Cells plasticity augments scar-free skin wound healing with hair growth. PLoS One 9:e93726PubMed PubMedCentral CrossRef
  Sampson S, Botto-van BA, Aufiero D (2013) Autologous bone marrow concentrate: review and application of a novel intra-articular orthobiologic for cartilage disease. Phys Sportsmed 41:7–18PubMed CrossRef
  Silva DN, de Freitas Souza BS, Azevedo CM et al (2014) Intramyocardial transplantation of cardiac mesenchymal stem cells reduces myocarditis in a model of chronic Chagas disease cardiomyopathy. Stem Cell Res Ther 5:81PubMed PubMedCentral CrossRef
  Srisawat N, Murugan R, Kellum JA (2014) Repair or progression after AKI: a role for biomarkers? Nephron Clin Pract 127:185–189PubMed CrossRef
  Tsuda H, Yamahara K, Otani K et al (2014) Transplantation of allogenic fetal membrane-derived mesenchymal stem cells protects against ischemia/reperfusion-induced acute kidney injury. Cell Transplant 23:889–899PubMed CrossRef
  Wu SM, Chiu HC, Chin YT et al (2014a) Effects of enamel matrix derivative on the proliferation and osteogenic differentiation of human gingival mesenchymal stem cells. Stem Cell Res Ther 5:52PubMed PubMedCentral CrossRef
  Wu Y, Cao Y, Li X et al (2014b) Cotransplantation of haploidentical hematopoietic and umbilical cord mesenchymal stem cells for severe aplastic anemia: successful engraftment and mild GVHD. Stem Cell Res 12:132–138PubMed CrossRef
  
• 作者单位：Huiling Cao (1)
  Qian Hui (2)
  Yongmin Yan (2)
  Chunbing Zhang (1)
  Xuewen Yang (1)
  Liang Ge (1)
  Wenrong Xu (2)
  
  1. Department of Laboratory Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Traditional Chinese Medicine, Nanjing, Jiangsu, 210029, People’s Republic of China
  2. Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, 212013, People’s Republic of China
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Life Sciences
  Microbiology
  Biotechnology
  Applied Microbiology
  Biochemistry
  
• 出版者：Springer Netherlands
• ISSN：1573-6776

文摘

Objective Human umbilical cord mesenchymal stem cells (hUCMSCs) have renoprotective effects but the influence of the microenvironment on characteristics of hUCMSCs has not been well studied. Here, we investigate the effects of injury conditions on properties of hUCMSCs.