Beam-hardening artifacts on computed tomography images caused by lanthanum carbonate hydrate in a patient on dialysis

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• 作者：Hiromitsu Hayashi (1)
  Minoru Machida (1)
  Tetsuro Sekine (1)
  Hidenori Yamaguchi (1)
  Tomonari Kiriyama (1)
  Shin-ichiro Kumita (1)
  
• 关键词：CT ; Artifact ; Lanthanum carbonate hydrate
• 刊名：Japanese Journal of Radiology
• 出版年：2010
• 出版时间：May 2010
• 年：2010
• 卷：28
• 期：4
• 页码：322-324
• 全文大小：397KB
• 参考文献：1. Hiroyama C, Sakita Y, Johno I, Yasunaga K, Kitazawa Y. Overdosing of prescribed drug discoverd by abdominal X-ray firm. Jpn J Acute Med 1999;23:1672鈥?674.
  2. Taketomi-Takahashi A, Tsushima Y, Nakajima T, Takano A, Amanuma M, Endo K. Manetite ingested as a nutritional supplement: unexpected source of MRI susceptibility artifact. AJR Am J Roentgenol 2007;188:1026鈥?027. CrossRef
  3. Damment SJP, Pennick M. Clinical pharmacokinetics of the phosphate binder lanthanum carbonate. Clin Pharmacokinet 2008;47:553鈥?63. CrossRef
  4. Persy VP, Behets GJ, Bervoets AR, De Broe ME, D鈥橦aese PC. Lanthanum: a safe phosphate binder. Semin Dial 2006;19:195鈥?99. CrossRef
  5. Shigematsu T, the Lanthanum Carbonate Group. Multicenter prospective randomized, double-blind comparative study between lanthanum carbonate and calcium carbonate as phosphate binders in Japanese hemodialysis patients with hyperphosphatemia. Clin Nephrol 2008;70:404鈥?10.
  6. Singanamala S, Roer DA, Perazella MA. An unexpected finding on chest roentgenogram following hemodialysis catheter placement. Semin Dial 2008;21:296鈥?94. CrossRef
  7. Chuang CL, Chiou SY, Li SY, Jian DY, Chen JY. A peritoneal dialysis patient with an unusual abdominal film. Kidney Int 2007;72:1291鈥?292. CrossRef
  8. David S, Kirchhoff T, Haller H, Meier M. Heavy metal rely on gut feelings: novel diagnostic approach to test drug compliance in patients with lanthanum intake. Nephrol Dial Transplant 2007;22:2091鈥?092. CrossRef
  9. Pafcugov谩 J, Hor谩ckov谩 M, Hraskov谩 M, Forejt J, Szabo M, P谩dr R. Radio-opaque appearance of lanthanum carbonate in a patient with chronic renal failure. Nephrol Dial Transplant 2008;23:1776鈥?778. CrossRef
  
• 作者单位：Hiromitsu Hayashi (1)
  Minoru Machida (1)
  Tetsuro Sekine (1)
  Hidenori Yamaguchi (1)
  Tomonari Kiriyama (1)
  Shin-ichiro Kumita (1)
  
  1. Department of Radiology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8602, Japan
  

文摘

Lanthanum carbonate hydrate is a nonaluminum, noncalcium phosphate binder containing lanthanum (La). It is effective in decreasing the serum phosphate level in patients on dialysis. Because the atomic number of the La contained in lanthanum carbonate hydrate is relatively high, at 57, this agent may cause strong artifacts on computed tomography (CT) images, which may be mistakenly interpreted as foreign bodies. We recently performed CT examination of a patient on Fosrenol chewable tablets (i.e., lanthanum carbonate hydrate). The CT images were difficult to evaluate because of strong beam hardening artifacts, and differentiation from foreign body aspiration was required. We report here our experience and a discussion of the characteristics of this artifact.