Resolution of diarrhea in an immunocompromised patient with chronic norovirus gastroenteritis correlates with constitution of specific antibody blockade titer

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• 作者：Bettina M. Knoll ; Lisa C. Lindesmith ; Boyd L. Yount ; Ralph S. Baric…
• 刊名：Infection
• 出版年：2016
• 出版时间：August 2016
• 年：2016
• 卷：44
• 期：4
• 页码：551-554
• 全文大小：449 KB
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Infectious Diseases
  General Practice and Family Medicine
  Internal Medicine
  
• 出版者：Urban & Vogel
• ISSN：1439-0973
• 卷排序：44

文摘

Norovirus gastroenteritis in immunocompromised hosts can result in a serious and prolonged diarrheal illness. We present a case of chronic norovirus disease during rituximab-bendamustine chemotherapy for non-Hodgkin’s lymphoma. We show for the first time a correlation between norovirus strain-specific antibody blockade titers and symptom improvement in an immunocompromised host.KeywordsNorovirusStrain-specific antibody blockade titersImmunocompromised host