Helicobacter pylori prevalence and clinical significance in patients with quiescent Crohn’s disease

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• 作者：Adi Lahat ; Uri Kopylov ; Sandra Neuman ; Nina Levhar…
• 关键词：Crohn’s disease ; Helicobacter pylori ; Video capsule endoscopy ; Prevalence ; Eradication
• 刊名：BMC Gastroenterology
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：17
• 期：1
• 全文大小：673KB
• 刊物主题：Gastroenterology; Internal Medicine; Hepatology;
• 出版者：BioMed Central
• ISSN：1471-230X
• 卷排序：17

文摘

BackgroundHelicobacter pylori (HP) infection is present in about 50% of the global population, and is associated with chronic gastritis, peptic disease and gastric malignancies. HP prevalence in Crohn’s disease (CD) patients was shown to be low compared to the general population, and its influence on disease activity is yet to be determined. Our aims were to determine the prevalence of HP in a selected group of CD patients with quiescent disease, and to assess the influence of its eradication on disease activity and endoscopic and laboratory activity measures.