The anti-inflammatory effect of Cheongseoikki-tang ethanol extract on allergic reactions mediated by bone marrow-derived mast cells

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• 作者：Joon-Ho Keum (11448)
  Ok-Hwa Kang (11448) (21448)
  Sung-Bae Kim (11448)
  Su-Hyun Mun (11448)
  Yun-Soo Seo (11448)
  Ma-Ryong Kim (11448)
  Jung-Rae Rho (21448)
  Young-Seob Lee (31448)
  Chung-Berm Park (31448)
  Young-Guk Kim (31448)
  Yong-Il Kim (31448)
  sin-Hee Han (31448)
  Dong-Yeul Kwon (11448)
  
• 关键词：Cheongseoikki ; tang ethanol extract ; bone marrow ; derived mast cell ; allergy ; interleukin ; 6 ; prostaglandin D2 ; leukotriene C4
• 刊名：Chinese Journal of Integrative Medicine
• 出版年：2013
• 出版时间：May 2013
• 年：2013
• 卷：19
• 期：5
• 页码：380-386
• 全文大小：461KB
• 参考文献：1. Fuwa T, Kosoto H, Tani T. Use of crude drugs in “PiWeiLun-in comparison to those used in “NeiWaiShangBianHuoLun.-Yakushigaku Zasshi 2005;40(1):13-1.
  2. Lee K, Jeong W. Effects of Cheongseoikgitang on the recovery of damaged liver in rat. Kor J Oriental Med Pathol 1991;6:111-26.
  3. Stevens RL, Austen KF. Recent advances in the cellular and molecular biology of mast cells. Immunol Today 1989;10:381-86. CrossRef
  4. Yamaguchi M, Sayama K, Yano K, Lantz CS, Noben-Trauth N, Ra C, et al. IgE enhances Fc epsilon receptor I expression and IgE-dependent release of histamine and lipid mediators from human umbilical cord blood-derived mast cells: synergistic effect of IL-4 and IgE on human mast cell Fc epsilon receptor I expression and mediator release. J Immunol 1999;162:5455-65.
  5. Murakami M, Kudo I. Diversity and regulatory functions of mammalian secretory phospholipase A2s. Adv Immunol 2001;77:163-94. CrossRef
  6. Chae HS, Chin YW. Anti-allergic effect of lambertianic acid from Thuja orientalis in mouse bone marrow-derived mast cells. Immunopharmacol Immunotoxicol 2012;34:250-55. CrossRef
  7. O’Banion MK, Winn VD, Young DA. cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase. Proc Natl Acad Sci USA 1992;89:4888-892. CrossRef
  8. Crofford LJ. COX-1 and COX-2 tissue expression: implications and predictions. J Rheumatol Suppl 1997;49:15-9.
  9. Kanaoka Y, Boyce JA. Cysteinyl leukotrienes and their receptors: cellular distribution and function in immune and inflammatory responses. J Immunol 2004;173:1503-510.
  10. Tokita K, Uchida Y, Yamamoto T. Roles of leukocytosis and cysteinyl leukotriene in polymorphonuclear leukocyte dependent plasma extravasation. J Leukoc Biol 2006;80:1308-319. CrossRef
  11. Yang JH, Son KH, Son JK, Chang HW. Anti-allergic activity of an ethanol extract from / Salviae miltiorrhiza. Arch Pharm Res 2008;31:1597-603. CrossRef
  12. Boehme SA, Franz-Bacon K, Chen EP, Ly TW, Kawakami Y, Bacon KB. Murine bone marrow-derived mast cells express chemoattractant receptor-homologous molecule expressed on T-helper class 2 cells (CRTh2). Int Immunol 2009;21:621-32. CrossRef
  13. Masferrer JL, Seibert K. Regulation of prostaglandin synthesis by glucocorticoids. Receptor 1994;4(1):25-0.
  14. Mitchell JA, Akarasereenont P, Thiemermann C, Flower RJ, Vane JR. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci USA 1993;90:11693-1697. CrossRef
  15. Seibert K, Masferrer JL. Role of inducible cyclooxygenase (COX-2) in inflammation. Receptor 1994;4(1):17-3.
  16. Chae HS, Kang OH, Oh YC, Choi JG, Keum JH, Kim SB, et al. Gomisin N has anti-allergic effect and inhibits inflammatory cytokine expression in mouse bone marrowderived mast cells. Immunopharmacol Immunotoxicol 2011;33:709-13. CrossRef
  17. Geuenich S, Haberl C, Egger D, Kaspers U, Hültner L, Wilmanns W, et al. Induction of leukotriene production by bleomycin and asparaginase in mast cells / in vitro and in patients / in vivo. Biochem Pharmacol 1998;55:447-53. CrossRef
  18. Naka T, Nishimoto N, Kishimoto T. The paradigm of IL-6: from basic science to medicine. Arthritis Res 2002;4 Suppl 3:S233–S242. CrossRef
  19. Ministry of Health and Welfare, Republic of Korea. Prescription medicine provisions on the type and preparation methods. 1995.
  20. Cho SH, Yao Z, Wang S-W, Alban RF, Barbers RG, French SW, et al. Regulation of activin A expression in mast cells and asthma: its effect on the proliferation of human airway smooth muscle cells. J Immunol 2003;170:4045-052.
  21. Levi-Schaffer F, Riesel N, Soffer D, Abramsky O, Brenner T. Mast cell activity in experimental allergic encephalomyelitis. Mol Chem Neuropathol 1991;15:173-84. CrossRef
  22. Xie W, Du L. Diabetes is an inflammatory disease: evidence from traditional Chinese medicines. Diabetes Obes Metab 2011;13:289-01. CrossRef
  23. Zhu XY, Cheng GL, Liu FH, Yu J, Wang YJ, Yu TQ, et al. Taguchi approach for anti-heat stress prescription compatibility in mice spleen lymphocytes / in vitro. Arch Pharm Res 2011;34:1125-133. CrossRef
  24. Ahn BS, Yang M, Jang H, Lee HJ, Moon C, Kim JC, et al. Evaluation of the antiosteoporotic potential of cimicifuga heracleifolia in female mice. Phytother Res 2011;26:663-68. CrossRef
  25. Song B, Lee E, Kim H, Jin S, Kim S, Kim D. Effects of Astrgali Radix on the function of murine immunocytes / in vivo and / in vitro. Kor J Herbology 1998;13:115-28.
  26. Sung H, Choi Y, Cho S, Lee H, Choi S. Effects of methanol extracts of / Rubus Coreanus Miquel and / Atractylodes Japonica Koidzumi on hepatic toxicity and immunomodulating activity in mice. Nutr Sci 2006;9(2):68-3.
  27. Jeong SI, Kim SY, Kim SJ, Hwang BS, Kwon TH, Yu KY, et al. Antibacterial activity of phytochemicals isolated from / Atractylodes japonica against methicillin-resistant / Staphylococcus aureus. Molecules 2010;15:7395-402. CrossRef
  28. Xian YF, Mao QQ, Ip SP, Lin ZX, Che CT. Comparison on the anti-inflammatory effect of / Cortex Phellodendri Chinensis and / Cortex Phellodendri Amurensis in 12-O-tetradecanoylphorbol-13-acetate-induced ear edema in mice. J Ethnopharmacol 2011;137:1425-430. CrossRef
  29. Fong CC, Wei F, Chen Y, Yu WK, Koon CM, Leung PC, et al. Danshen-Gegen decoction exerts proliferative effect on rat cardiac myoblasts H9c2 via MAPK and insulin pathways. J Ethnopharmacol 2011;138(1):60-6. CrossRef
  30. Lee YC, Lee JC, Seo YB, Kook YB. Liriopis tuber inhibit OVA-induced airway inflammation and bronchial hyperresponsiveness in murine model of asthma. J Ethnopharmacol 2005;101(1-):144-52. CrossRef
  31. Jang YJ, Kim ME, Ko SY. n-Butanol ext racts of Panax notoginseng suppress LPS-induced MMP-2 expression in periodontal ligament fibroblasts and inhibit osteoclastogenesis by suppressing MAPK in LPS-activated RAW264.7 cells. Arch Oral Biol 2011;56:1319-327. CrossRef
  32. Baravalle C, Dallard BE, Cadoche MC, Pereyra EAL, Neder VE, Ortega HH, et al. Proinflammatory cytokines and CD14 expression in mammary tissue of cows following intramammary inoculation of / Panax ginseng at drying off. Vet Immunol Immunopathol 2011;144(1-):52-0. CrossRef
  33. Tanabe S, Kinuta Y, Yasumatsu H, Takayanagi M, Kobayashi S, Takido N, et al. Effects of / Citrus unshiu powder on the cytokine balance in peripheral blood mononuclear cells of patients with seasonal allergic rhinitis to pollen. Biosci Biotechnol Biochem 2007;71:2852-855. CrossRef
  34. Kobayashi S, Tanabe S. Evaluation of the anti-allergic activity of / Citrus unshiu using rat basophilic leukemia RBL-2H3 cells as well as basophils of patients with seasonal allergic rhinitis to pollen. Int J Mol Med 2006;17:511-15.
  35. Kubo M, Matsuda H, Tomohiro N, Yoshikawa M. Studies on / Alismatis rhizoma I anti-allergic effects of methanol extract and six terpene components from / Alismatis rhizoma (dried rhizome of / Alisma orientale). Biol Pharm Bull 1997;20:511-16. CrossRef
  36. Joo SS, Park D, Shin S, Jeon JH, Kim TK, Choi YJ, et al. Anti-allergic effects and mechanisms of action of the ethanolic extract of / Angelica gigas in dinitrofluorobenzeneinduced inflammation models. Environ Toxicol Pharmacol 2010;30:127-33. CrossRef
  37. Shin EM, Zhou HY, Guo LY, Kim JA, Lee SH, Merfort I, et al. Anti-inflammatory effects of glycyrol isolated from / Glycyrrhiza uralensis in LPS-stimulated RAW264.7 macrophages. Int Immunopharmacol 2008;8:1524-532. CrossRef
  38. Kay AB. Overview of “allergy and allergic diseases: with a view to the future- Br Med Bull 2000;56:843-64. CrossRef
  39. Fiorucci S, Meli R, Bucci M, Cirino G. Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in anti-inflammatory therapy Biochem Pharmacol 2001;62:1433-438. CrossRef
  40. Kitamura Y. Recent progress of mast cell research. Arerugi 2005;54(2):45-7.
  
• 作者单位：Joon-Ho Keum (11448)
  Ok-Hwa Kang (11448) (21448)
  Sung-Bae Kim (11448)
  Su-Hyun Mun (11448)
  Yun-Soo Seo (11448)
  Ma-Ryong Kim (11448)
  Jung-Rae Rho (21448)
  Young-Seob Lee (31448)
  Chung-Berm Park (31448)
  Young-Guk Kim (31448)
  Yong-Il Kim (31448)
  sin-Hee Han (31448)
  Dong-Yeul Kwon (11448)
  
  11448. College of Pharmacy and Wonkwang Oriental Medicines Research Institute, Wonkwang University, Jeonbuk, 570-749, Republic of Korea
  21448. Department of Oceanography, Kunsan National University, Kunsan, 573-701, Republic of Korea
  31448. National Institute of Horticultural & Herbal Science, RDA, Eumsung, 369-873, Republic of Korea
  

文摘

Objective Cheongseoikki-tang (CIT, Korean), also called Qingshu Yiqi decoction ( and Seisho-ekki-to (Japanese), is well known as an effective traditional combination of herbs for treating cardiovascular diseases. This study was to research its effects on bone marrow-derived mast cell (BMMC)-mediated allergy and inflammation mechanisms. Methods In this study, the biological effect of Cheongseoikki-tang ethanol extract (CITE) was evaluated, focusing on its effects on the production of allergic mediators by phorbol 12-myristate 13-acetate (PMA) plus calcium ionophore A23187 (A23187)-stimulated BMMCs. These allergic mediators included interleukin-6 (IL-6), prostaglandin D2 (PGD2), leukotriene C4 (LTC4), and β-hexosaminidase (β-hex). Results Our data revealed that CITE inhibited the production of IL-6, PGD2, LTC4, and β-hex induced by PMA plus A23187 (P<0.05). Conclusion These findings indicate that CITE has the potential for use in the treatment of allergy.