?Schweinegrippe-vs. Brugada-Syndrom

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• 作者：K. Zindler ; K. Klingel ; T. Kriebel ; C. Marschall ; L.A. Ormandy…
• 关键词：H1N1 ; Viren ; Mutation ; Fieber ; Histologie ; Todesursache ; H1N1 virus ; Mutation ; Fever ; Histology
• 刊名：Rechtsmedizin
• 出版年：2015
• 出版时间：August 2015
• 年：2015
• 卷：25
• 期：4
• 页码：309-312
• 全文大小：605 KB
• 参考文献：1.Antzelevitch C (2006) Brugada syndrome. Pacing Clin Electrophysiol 29(10):1130-159PubMed Central PubMed View Article
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• 作者单位：K. Zindler (1)
  K. Klingel (2)
  T. Kriebel (3)
  C. Marschall (4)
  L.A. Ormandy (1)
  W. Grellner (1)
  
  1. Abteilung Rechtsmedizin, Universit?tsmedizin G?ttingen, G?ttingen, Deutschland
  2. Abteilung für Molekulare Pathologie, Universit?tsklinikum Tübingen, Tübingen, Deutschland
  3. Klinik für P?diatrische Kardiologie und Intensivmedizin, Universit?tsmedizin G?ttingen, G?ttingen, Deutschland
  4. Zentrum für Humangenetik und Laboratoriumsmedizin Martinsried, Martinsried, Deutschland
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Forensic Medicine
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1434-5196

文摘

The case presented concerns the sudden death of a 16-year-old boy who 2- days previously had suffered from a seasonal influenza infection. At autopsy and using additional tests an acute H1N1 (“swine flu- infection was diagnosed by histological and virological tests. As an incidental finding structural changes in the heart were additionally identified. The subsequent molecular pathological examinations revealed a mutation in the SCN5A gene, a region typical for Brugada syndrome, which has not been described in the literature before.