Naringin, a natural dietary compound, prevents intestinal tumorigenesis in Apc Min/+ mouse model

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• 作者：Yu-Sheng Zhang ; Ye Li ; Yan Wang ; Shi-Yue Sun…
• 关键词：Naringin ; Apc Min/+ mouse model ; Intestinal adenomatous polyps ; APC/β ; catenin signaling pathway ; Anti ; proliferation ; Apoptosis ; Anti ; inflammation
• 刊名：Journal of Cancer Research and Clinical Oncology
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：142
• 期：5
• 页码：913-925
• 全文大小：11,749 KB
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• 作者单位：Yu-Sheng Zhang (1)
  Ye Li (2)
  Yan Wang (3)
  Shi-Yue Sun (4)
  Tao Jiang (5)
  Cong Li (4)
  Shu-Xiang Cui (4)
  Xian-Jun Qu (1) (4)
  
  1. School of Pharmaceutical Sciences, Shandong University, Jinan, China
  2. Department of Pharmacology, School of Chemical Biology & Pharmaceutical Sciences, Capital Medical University, Beijing, China
  3. Department of Pharmacology, Institute of Materia Medica, Shandong Academy of Medical Sciences, Jinan, China
  4. Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, China
  5. Shandong Tumor Hospital, Jinan, China
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Oncology
  Cancer Research
  Internal Medicine
  Hematology
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-1335

文摘

Purpose Naringin is a natural dietary flavonoid compound. We aimed to evaluate the effects of naringin on intestinal tumorigenesis in the adenomatous polyposis coli multiple intestinal neoplasia (Apc Min/+) mouse model.